This is a hallucinogenic image of Edna Krabappel (not Crandall), Bart Simpson's perpetual fourth grade teacher. In the episode "El viaje misterioso de nuestro Jomer," Homer eats Guatemalan insanity peppers at a chili cook-off and goes on a psychedelic journey. When he looks at the already grotesque Springfieldians while tripping, they appear even more distorted. This is an interpretation of the image of Edna Krabappel in that episode. When she speaks, she sounds like one of the off-screen adults in the animated Charlie Brown films: "Wauh wauh wauh-wauh. Wauh wauhh. Wauhhhh."
As Robert "Sideshow Bob" Underdunk Terwilliger once said, "You only get one chance with Edna Krabappel." I have now had my chance.
An image of Edna from the episode. I thought she needed a sixth eye to make her symmetrical.